Genome sequencing
The company’s genome sequencing services help meet a wide range of research goals. Our genome sequencing services include projects that require re-sequencing to compare samples to a reference genome, as well as projects that require de novo sequencing to generate quality reference genomes of rarely sequenced species.
Whole genome sequencing (WGS) , focused on resequencing, can be used in a wide range of research, including evolutionary biology, developmental biology, agriculture, microbiology, and biomedical research.
Our new Whole Genome Sequencing service provides genome assembly and annotation for species that have either never been sequenced before, or species with missing or incomplete reference genomes.
Targeted resequencing services can be a cost-effective alternative for in-depth analysis of a selected region of a gene, such as WES (Whole Exome Sequencing) for studying exomes (protein-coding regions of the genome) or TRS (Targeted Region Sequencing) for studying a selected set of genes or genomic regions.
BioProject Human 1000 Year’s Life:
BioProject Human 1000 Year’s Life
Our FIRST GOAL is that the code includes DNA, as well as the “action code,” the RNA and proteins that actually make cells work.Over time, this activity deteriorates as we age. So we need to create effective metrics that can shed light on exactly what’s going on inside your cells.Once measured, we’ll need to return the code to its youthful state.
Replisome. Replication.
RR+ DNA editing during DNA replication.
Pipeline:
Return Life
Creating drugs for regeneration:
Regeneration-related Genes:
Our second goal: Currently, I know of 192,087 genes in the human genome. They can be edited. We are one of the first to master gene programming. There is AI in the genius of engineering that we are developing. Our main goal is to make life longer. The library says that Adam once lived for 1,000 years. Why not fix the genome and live for 1,000 or more years.
AGNEC – book life
(A) – Adeninom
(G) – Guanine
(N) – Nucleotide
(E) – Etyminom/uratsylon
(C) – Tsytozyn
Aging-related gene sets:
Pipeline:
Leaf of a hearty life. 200 Years.
Leaf of a hearty life. 500 Years.
Leaf of a hearty life. 1000 Years.
Our third goal: Each neuron in the brain is also a corresponding gene. How can you improve to be smarter. And for the brain to work at 100%.
Brain-region-specific genes are defined as those genes that are maximally expressed in each brain regions with τ > 0.9. As a consequence, 546 brain-region-specific genes of 12 brain regions are identified.
Pipeline:
The intelligence of life
| Brain Region: | All Cerebellum (177) Cerebellar Hemisphere (140) Spinal cord (cervical c-1) (139) Hypothalamus (34) Nucleus accumbens (basal ganglia) (23) Substantia nigra (14) Frontal Cortex (BA9) (6) Cortex (5) Hippocampus (4) Putamen (basal ganglia) (2) Amygdala (1) Caudate (basal ganglia) (1) |
PUBLICATIONS:
Korolov Y.O. MECHANISMS OF REGENERATIVE MEDICINE USING PRIMARY NULL NEURAL STEM CELLS.
Korolov Y.O. POLYPS REGENERATE, WE DON’T: HYDRA’S CELLULAR AND MOLECULAR REGENERATION SYSTEM.
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